氯化铁(III) 六水合物_250G

Application

Iron(III) chloride hexahydrate may be employed as an oxidant for the following conversions: 
• Synthesis of 2-substituted 4(3H)-quinazolinones (yield = 77-93%), via condensation of aldehydes with anthranilamide.^[1]
• Oxidation of 1,4-dihydropyridines (1,4-DHPs) to corresponding pyridines.^[3] 
• Oxidation of 4-isopropyl-1,4-DHP to dealkylated pyridine.^[3]

General description

Iron(III) chloride hexahydrate can be obtained from crystallization of iron(III) chloride from water. Its crystal structure has been studied using three-dimensional single-crystal X-ray-diffraction data. Its crystals have two chloride ions and four water molecules arranged around each ferric ion to form octahedral trans-[FeCl₂(OH₂)₄]⁺ ions having C_2h-2/msymmetry.^[2]